Guoqing Jia Associate Professor, Ph.D.
State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics
Chinese Academy of Sciences, Dalian 116023, China
Tel: 86-411-84379302
学习和工作经历：
2015.11-2016.10, 荷兰Utrecht大学, Bijvoet生物分子研究中心, 访问学者 2012.12-至今, 中国科学院大连化学物理研究所, 催化基础国家重点实验室, 副研究员 2010.7-2012.12, 中国科学院大连化学物理研究所, 催化基础国家重点实验室, 助理研究员 2002.9-2010.1,中国科学院大连化学物理研究所,物理化学,博士,导师:李灿 1999.9-2001.7,山西大学,英语,学士 1998.9-2002.7,山西大学,化学教育,学士
研究方向：
（1）DNA催化（DNA catalysis）：发现和认识DNA的催化（或化学）功能研究，致力于将这种功能与生物过程相关联，从催化化学的角度阐述DNA可能的生物学功能。 （2）生物分子的拉曼光谱研究（Raman spectroscopic characterization on Biomolecules）利用拉曼光谱及手性拉曼光谱研究溶液状态下核酸、糖、蛋白等生物分子的结构； （3）拉曼光谱技术在医药领域的应用研究（Application of Raman Spectroscopy in medicine and pharmacy）。
代表性成果： (1) Enantioselective induction by G-quadruplex DNA/hemin in intramolecular cyclopropanation, Wenhui Miao#, Jingya Hao#, Wenqin Zhou, Guoqing Jia*, and Can Li*, Chinese Journal of Catalysis, 2025, 78, 138-143. (2) G-quadruplex DNA/iron cationic porphyrin catalyzes enantioselective carbo-silicon bond formation, Wenhui Miao, Wenqin Zhou, Guoqing Jia*, and Can Li*, Chemical Communications, 2025, 61, 19640-19643. (3) Dopamine oxidation promoted by human telomeric DNA models in the presence of a Cu(ii) terpyridine chelate, Yu Bao, Wenqin Zhou, Wenhui Miao, Guoqing Jia*, and Can Li*, Chemical Communications, 2024,60, 1172-1175. (4) Cationic porphyrin mediated G-Quadruplex DNA oxidative damage: regulated by the initial interplay between DNA and TMPyP4, Wenqin Zhou, Yu Cheng, Bo Song, Jingya Hao, Wenhui Miao, Guoqing Jia*, and Can Li*, Biochemistry, 2021, 60, 707-3713. (5) Stereostructural elucidation of glucose phosphorylation by Raman Optical Activity. Yuxuan Tang#, Feng Cheng#, Zhaochi Feng, Guoqing Jia*, and Can Li*, Journal of Physical Chemistry B，2019, 123, 7794-7800. (6) Terpyridine-Cu(II) targeting human telomeric DNA to produce highly stereospecific G-quadruplex DNA metalloenzyme. Yinghao Li, Mingpan Cheng, Jingya Hao, Changhao Wang, Guoqing Jia*, and Can Li*, Chemical Science 2015, 6, 5578-5585. (as of 01/14/2026)
|
