Nagwa Nawar

Professor of Inorganic Chemistry, Chemistry Department,
Faculty of Science, Mansoura University, Mansoura, Egypt.

Email:nnawar@mans.edu.eg

Scientific Qualifications

  • 1979: B.Sc. in Chemistry, Mansoura University, Egypt.
  • 1983: M.Sc. in Inorganic Chemistry, Mansoura University, Egypt.
    Thesis entitled "Physico-Chemical Studies On Some Hydrazone Derivatives And Their Complexes With Some Transition Metal Ions".
  • 1989: Ph.D. University of Liverpool, U.K.
    Thesis title "Synthesis, Reactions and Catalytic Studies of Homo - and Heterometallic Complexes Using Bi - and Tri - dentate Phosphine Ligands".
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    Research field:

    My work focuses on aspects of organometallic and coordination chemistry. The research interest is concerned with finding new routes for the synthesis of complexes containing hetero-nuclear metal-metal bonds and investigating the reactivity of these complexes. Also, studying the reactions of unsaturated organic groups with metal clusters in order to try to understand how changing the electronic properties of the cluster can vary the reactivity. This work has important implications concerning the mechanisms of heterogeneous and homogeneous catalysis.

    Also, I’m interested to study the interactions between transition metal complexes and DNAs or in general their biological activities. It is related to the development of novel reagents for biotechnology and medicine. Transition metal complexes have been widely exploited for these applications due to their unique spectral and electrochemical signatures. In addition, one important reason for such study is that by changing their ligand environment one can tune the DNA binding and cleaving ability of a metal complex.

    Recently, we worked on metal complexes derived from for example thiourea derivatives containing amino acids are receiving much attention since these complexes have antitumor, anticancer, antimalarial, anti-inflammatory, and anti-influenza activities. Few studies have been reported on the derivatives of the thiourea compounds derived from methionine. The importance of both methionine and the thiourea residues in the same ligand gives us the push to study this type of ligand. Moreover, the wide application of thiourea and amino acid derivatives is another reason to continue to study this class of compounds. We extend this work to include the complexes derived from carboxylmethylthiopropylidine thiourea and its metal complexes with Cu(II), Co(II), Ni(II), Zn(II), and Fe(III) salts.

    Also, the investigation of thiosemicarbazones and their metal complexes has been carried out in our laboratory and the ligand and its Pd(II) complex shows antimicrobial activity against both Micrococcus sp. and B. subtilis.

    Publications:

    1. Syntheses of Iron-Containing Hetrometallic Complexes Using Tridentate Phosphine Ligands, The Crystal Structure of [(OC)3Fe{(Ph2P)2CHCH2PPh2}Ru3(CO)9{Ph2PC(CH2)PPh2}], J. Chem. Soc. Dalton Trans, 2939-2942 (1992).

    2. Syntheses of Ruthenium-Containing Heterometallic Complexes by Use of Tridentate Phosphine Ligands, J. of Organometallic Chemistry, 493, 239-242 (1995).

    3. W2Cl4(NR2)2(NR’3)2 Molecules. 4. A New Synthetic Route to Products with a Staggered Conformation. Preparations and Characterizations of W2Cl4(NR2)2(NR’3)2 (R = Et, Bu, Hex; R’3 = Me3, Et2H) and an Intermediate Complex W2Cl4(NEt2)2(NHEt2)2, Inorganic Chemistry, 36(4), 559-566 (1997).

    4. Transition Metal Complexes of 2-Acetylpyridine o-Hydroxybenzoyl hydrazone (APo-OHBH): Their Preparation, Characterization and Antimicrobial Activity, Chem. Pharm. Bull. (Japan), 47(7), 944-949 (1999).

    5. Iridium Carbonyl Cluster Complexes with Bidentate Phosphine Ligands; The X-Ray Crystal Structure of [Ir4(CO)8(dppa)2].3(THF), J. of Organomet. Chemistry, 602, 137-143 (2000).

    6. Mono- and Binuclear Schiff Base Complexes Derived From Glycine, 3-Acetylpyridine and Transition Metal Ions, Transition Metal Chemistry, 26, 180-185 (2001).

    7. Preparation and characterization of chelating fibers based on natural wool for removal of Hg(II), Cu(II) and Co(II) metal ions from aqueous solutions, Journal of Hazardous Materials, 184, (I-3), 2010, 118-125.

    8. Preparation and characterization of chitosan-grafted-poly(2-amino-4,5-pentamethylene-thiophene-3-carboxylic acid N-acryloyl-hydrazide) chelating resin for removal of Cu(II), Co(II) and Ni(II)metal ions from aqueous solutions, International Journal of Biological Macromolecules, 48 (2011) 558–565.

    9. Synthesis and spectral characterization of some metal complexes derived from n-benzoyl-n--carboxyl methylthiopropylidine thiourea (bcmt), Phosphorus Sulfur and Silicon and the Related Elements, 187 (8), 976-989, 2012.

    10. Removal of heavy metals Fe3+, Mn2+, Zn2+, Pb2+ and Cd2+ from wastewater by using rice straw as low cost adsorbent, Submitted to be presented and published in ICSTE2013 at Michael Okpara University of Agriculture, Umudike-Abia State, Nigeria, August 12-15, 2013.