Wengang Guo (郭文岗), Ph.D.

Date of birth: 1985 
Place of birth: Hejin city of Shanxi province 
State Key Laboratory of Catalysis, Dalian Institute of 
Chemical Physics, Chinese Academy of Sciences (CAS), 
Dalian, 116023, P. R. China 
E-mail: wgguo@dicp.ac.cn

 

Work Experience: 
5/2016 to present, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, P. R. China. 

Education: 
2010 – 2016, State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, P. R. China. 
Ph.D. in Physical Chemistry 
2006 – 2010, College of Chemical & Chemical Engineering, Shanxi University, P. R. China. 
B.S. in Applied Chemistry. 

Research Interests: 
Organocatalytic Asymmetric Synthesis: 

1. Asymmetric nucleophilic catalysis ( e.g., Amino catalysis, NHC catalysis );
2. Bronsted base catalysis (e.g., chiral bifunctional thiourea/squaramide catalysis);
3. Bronsted acid catalysis (e.g., chiral phosphoric acid catalysis)

Representative Publications:

1.Wengang Guo, Bo Wu, Xin Zhou, Ping Chen, Xu Wang, Yonggui Zhou, Yan Liu*, Can Li*.
Formal asymmetric catalytic thiolation with a bifunctional catalyst at a water-oil interface: synthesis of benzyl thiols.
Angew. Chem. Int. Ed., 2015, 54, 4522-4526. 
 
2. Wengang Guo#, Xu Wang#, Boyu Zhang, Shuai Shen, Xin Zhou, Peng Wang, Yan Liu*, Can Li*.
Facile synthesis of chiral spirooxindole-based isotetronic acids and 5-1H-pyrrol-2-ones through cascade reactions with bifunctional organocatalysts. 
Chem. Eur. J. 2014, 20, 8545-8550 (# these authors contributed equally for this article). 
 
3. Wengang Guo, Jianwei Wei, Yan Liu*, Can Li*. 
Construction of anti-1,2-diols bearing chiral tertiary alcohol moiety using free hydroxyacetone as aldol donor by imidazole-based prolineamide catalyst. 
Tetrahedron, 2014, 70, 6561-6568.
 
4. Ping Cheng, Wengang Guo, Ping Chen, Yan Liu*, Xin Du*, Can Li*.
The enantioselective construction of chiral spirooxindole-based 4-thiazolidinone via asymmetric catalytic formal [3+2] annulation using a bifunctional catalyst. 
Chem. Commun., 2016, 52, 3418-3421.
5.Wengang Guo, Yan Liu*, and Can Li*. 
Asymmetric Catalytic 1,2-Hydroperoxidation of Isatin-Derived Ketimine with Hydrogen Peroxide in the Crowding Environment of PEGs.
Org. Lett., 2017, 19, 1044-1047 DOI: 10.1021/acs.orglett.7b00032

6.Wengang Guo, Xianghui Liu, Yan Liu*, and Can Li* Chiral Catalysis at the Water/Oil Interface (invited Perspective) ACS Catal., 2018, 8, 328?341